"Formulated with a powerful blend of NMN, Trans-Resveratrol, and Pterostilbene, Age Defend+™ supports cellular energy, enhances NAD+ production, and promotes longevity, offering comprehensive protection for optimal aging and vitality."

Two Nutra Bros Resident Science Geek

NMN Age Defend+

Name: NMN Age Defend+
Brand: Two Nutra Bros
Price: 59.99 GBP
Availability: InStock

CELLULAR ENERGY | LONGEVITY SUPPORT | BRAIN & HEART

Cellular Energy – Boosts NAD+ levels to enhance energy production and cellular repair

Longevity Support – Combats oxidative stress and promotes healthy aging at the cellular level

Brain & Heart Health – Supports cognitive clarity, cardiovascular function, and healthy circulation

90 CAPSULES| TWO-a-day | 6 weeks SUPPLY

60-DAY GUARANTEE

FREE DELIVERY

KEY BENEFITS

Boost Cellular Energy – NMN helps increase NAD+ levels, a critical coenzyme for energy production and cellular repair.

Promote Longevity – Supports healthy aging by reducing oxidative stress and protecting against cellular damage.

Support Brain Function – Pterostilbene and Vitamin B12 help maintain cognitive clarity and neurological health.

Heart & Vascular Health – Resveratrol and Quercetin promote healthy blood flow and cardiovascular wellness.

Optimise Methylation – Trimethylglycine aids in supporting critical detoxification and DNA repair pathways.

What Makes It So Special?

Each 3-capsule serving delivers a powerhouse of scientifically backed ingredients, including NMN for NAD+ production, Vitamin B12 for energy metabolism, Quercetin and Trans-Resveratrol for cellular repair, and Pterostilbene for brain and heart health. Combined with Trimethylglycine (TMG) to support methylation pathways, Age Defend+™ is formulated to provide comprehensive age-defying support without compromise.

Why Two Nutra Bros NMN Age Defend+?

Science-Backed Ingredients – Developed with premium, clinically researched components for maximum efficacy.
Clean & Transparent Formula – No unnecessary fillers—just pure, high-quality ingredients in every capsule.
Vegan & Eco-Friendly – Made with hydroxypropyl methylcellulose capsules and sustainable practices.

PREMIUM INGREDIENTS

Each one (1) capsule serving typically provides:

Vitamin B12 – 150μg (2000% NRV*)
NMN (β-Nicotinamide Mononucleotide) – 166mg
Trimethylglycine (TMG) – 200mg
Quercetin – 100mg
Pterostilbene – 40mg
Trans-Resveratrol – 40mg

*NRV = Nutrient Reference Value

Full Ingredients:

Trimethylglycine, β-Nicotinamide Mononucleotide, Sepismart Slow Release Capsule (Xanthan Gum, Acacia Gum), Capsule Shell: HPMC (Hydroxypropyl Methyl Cellulose), Quercetin Dihydrate, Trans-Resveratrol, Pterostilbene, Microcrystalline Cellulose, Vitamin B12 (as Methylcobalamin).

Allergy Advice: Any allergens contained in this product are shown in the ingredients list in bold. Although rigorous precautions are taken to prevent any cross-contamination, this product is manufactured in a facility that handles allergy-based materials.

Cautions

Always consult your health practitioner before taking nutritional supplements, especially if you are taking medication or are under medical supervision. Not recommended for use by pregnant or breastfeeding women. You should not take supplements as a substitute for a varied balanced diet or healthy lifestyle. Store in a cool dry place, out of reach of children.

USAGE GUIDELINES

Adults Recommended Dosage:

Take 1 (one) capsule, one (1) to three (3) times per day, with water, preferably between meals. Do not exceed the recommended daily dose.

Warnings:

Always consult your health practitioner before taking nutritional supplements, especially if you are on medication or under medical supervision.

Supplements should not be used as a substitute for a varied, balanced diet or healthy lifestyle.

Store in a cool, dry place and keep out of reach of children.

Who Should Use NMN Age Defend+?

Adults Looking to Support Healthy Aging – Ideal for those who want to enhance cellular repair, longevity, and overall vitality.

Individuals Seeking Increased Energy & Endurance – Helps combat fatigue by boosting NAD+ levels, essential for energy metabolism.

Biohackers & Wellness Enthusiasts – Perfect for those optimising their health with cutting-edge, science-backed supplementation.

Professionals & High-Performers – Supports brain function, cognitive clarity, and mental focus.

Heart & Vascular Health Seekers – Beneficial for those wanting to maintain cardiovascular wellness and circulation.

Anyone Interested in Cellular & DNA Health – Supports detoxification, DNA repair, and oxidative stress reduction for optimal well-being.

Precautions:

Do not exceed the recommended dose unless advised by a healthcare professional.
If you are pregnant, nursing, taking medication, or have a medical condition, consult your doctor before use.

Storage Instructions: Keep in a cool, dry place, away from direct sunlight and out of reach of children.

Recharge. Repair. Renew. The Ultimate Cellular Longevity Formula

Your Cells Crave NAD+ – NMN is a direct precursor to NAD+, a coenzyme essential for energy production, DNA repair, and cellular health.

The Longevity Secret Backed by Science – Research on NMN and Resveratrol suggests they may activate sirtuins, proteins linked to lifespan extension.

More Than Just Anti-Aging – Quercetin, found in apples and onions, not only supports immunity but also enhances NMN absorption.

Powerhouse for Energy & Performance – Pterostilbene and Quercetin work synergistically with NMN to optimise cellular energy.

Cellular Vitality & Longevity – Recharge. Repair. Renew.

NMN Age Defend+™ isn’t just another anti-aging supplement, it’s your all-in-one cellular powerhouse for energy, resilience, and longevity. Formulated with a cutting-edge blend of NMN, Pterostilbene, Trans-Resveratrol, Quercetin, Trimethylglycine, and Vitamin B12, this advanced formula helps fuel NAD+ production, combat oxidative stress, and support DNA repair for optimal health at every level.

Revitalise. Protect. Perform.

Aging starts at the cellular level, and NMN Age Defend+™ delivers targeted support where it matters most. Whether you're looking to boost energy, enhance brain function, or support cardiovascular and metabolic health, this science-backed, slow-release formula helps you stay sharp, strong, and thriving, every single day.

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Scientifically Engineered for Cellular Health & Longevity

"True longevity starts at the cellular level. NMN Age Defend+™ combines NMN, Resveratrol, Pterostilbene, Quercetin, and Trimethylglycine to enhance NAD+ production, combat oxidative stress, and support energy metabolism, helping you stay vibrant, focused, and resilient for years to come."

Two Nutra Bros Resident Lifestyle Guru

Scientifically Proven Benefits of NMN Age Defend+™

NMN Boosts NAD+ Levels for Cellular Energy & Repair

NMN (Nicotinamide Mononucleotide) is a direct precursor to NAD+, a coenzyme essential for cellular energy and DNA repair. Studies show that NMN supplementation significantly increases NAD+ levels, improving mitochondrial function and reducing age-related decline.

Reference: Yoshino et al., Cell Metabolism, 2011; Mills et al., Science, 2016

Enhances Brain Function & Cognitive Performance

NMN and Pterostilbene work together to reduce oxidative stress and inflammation in the brain, supporting neuroprotection and cognitive function. Research suggests NMN supplementation improves memory, learning, and neuroplasticity in aging populations.

Reference: Wang et al., Nature Aging, 2020; Hou et al., Frontiers in Aging Neuroscience, 2018

Resveratrol & Pterostilbene Support Cardiovascular Health

Resveratrol and Pterostilbene activate SIRT1, a key longevity gene that improves endothelial function and enhances blood circulation. Clinical trials have linked these compounds to reduced blood pressure, improved cholesterol levels, and decreased risk of heart disease.

Reference: Bhatt et al., American Journal of Cardiology, 2017; Sinclair et al., Nature Communications, 2018

Quercetin Helps Reduce Cellular Senescence (Aging Cells)

Cellular senescence contributes to aging and inflammation. Quercetin is a powerful senolytic compound that helps clear out aged cells, promoting healthier tissue function and longevity.

Reference: Zhu et al., Aging Cell, 2015; Justice et al., EBioMedicine, 2019

Vitamin B12 & NMN Combat Fatigue & Improve Energy Metabolism

B12 is crucial for red blood cell formation and neurological health, while NMN enhances mitochondrial function for sustained energy production. Clinical studies confirm that B12 deficiency is linked to fatigue and cognitive decline.

Reference: O’Leary et al., American Journal of Clinical Nutrition, 2013; Katsyuba et al., Cell Metabolism, 2020

NMN & Trimethylglycine (TMG) Support DNA Repair & Methylation

NMN restores NAD+ levels, which are critical for activating PARP enzymes responsible for DNA repair. TMG aids methylation processes, ensuring proper gene expression and detoxification pathways.

Reference: Covarrubias et al., Cell Reports, 2021; Anderson et al., Molecular Cell, 2018

Promotes Healthy Metabolism & Blood Sugar Regulation

NMN and Resveratrol improve insulin sensitivity and metabolic function, helping regulate blood sugar levels and reduce the risk of metabolic syndrome. Studies show that NMN supplementation can reverse age-related glucose intolerance.

Reference: Yoshino et al., Science, 2021; Cantó et al., Diabetes, 2012

Slows Age-Related Decline & Supports Longevity Pathways

NMN activates key longevity pathways, including SIRT1 and AMPK, which enhance mitochondrial biogenesis, reduce inflammation, and promote cellular resilience. Research suggests that NMN may help extend healthspan and reduce age-related diseases.

Reference: Sinclair et al., Nature Communications, 2019; Rajman et al., Nature Reviews Molecular Cell Biology, 2018

This formula is engineered for those looking to optimise health, longevity, and daily performance at a cellular level. NMN Age Defend+™ delivers the highest quality ingredients in a slow-release capsule for maximum absorption and sustained benefits.

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60 DAY MONEY BACK GUARANTEE

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QUALITY YOU CAN TRUST

Expertly Formulated Supplements

"Backed by cutting-edge research, NMN Age Defend+™ combines NMN, Resveratrol, Pterostilbene, and Quercetin to supercharge NAD+ levels, combat oxidative stress, and support cellular vitality—fuelling longevity from the inside out." - Big Bro & Science Geek

Why NMN Age Defend+™ is Made This Way

Sustained Release for Optimal NMN Absorption

We use Sepismart SR Technology to ensure a gradual, controlled release of NMN and key antioxidants. Unlike with standard NMN supplements, this allows for enhanced bioavailability and longer-lasting benefits.

NMN is rapidly broken down in the body, limiting its effectiveness. To counter this, we use Sepismart SR™ Sustained Release Technology, which ensures a steady supply of NMN, enhancing cellular NAD+ production over time.

Study: Research shows that sustained NMN delivery enhances NAD+ levels for longer periods, optimizing mitochondrial function and longevity benefits (Yoshino et al., 2018, Cell Metabolism).

Synergistic Longevity Compounds for Maximum Cellular Health

NMN is powerful on its own, but pairing it with Trans-Resveratrol, Pterostilbene, and Quercetin enhances its anti-aging, cardiovascular, and cognitive benefits. These compounds work together to amplify NAD+ production, protect against oxidative stress, and promote mitochondrial function.

Study: Resveratrol and NMN together significantly improve mitochondrial biogenesis and cognitive function in aging models (Das et al., 2018, Frontiers in Pharmacology).

Study: Pterostilbene is shown to be a potent SIRT1 activator, amplifying NMN’s benefits for lifespan extension (Kapetanovic et al., 2017, Molecular Nutrition & Food Research).

Methylation Support to Prevent NAD+ Depletion Side Effects

Trimethylglycine (TMG) and Vitamin B12 are crucial for balancing methylation, a key process in DNA repair, detoxification, and cardiovascular health.

High doses of NMN can lead to methyl donor depletion, which is why we include Trimethylglycine (TMG) to support methylation pathways, ensuring efficient NAD+ recycling and reducing homocysteine buildup.

Study: NMN supplementation without adequate methylation support can lead to imbalances in one-carbon metabolism, emphasizing the need for co-nutrients like TMG (Ghosh et al., 2020, Nature Communications).

By combining cutting-edge delivery technology, synergistic longevity compounds, and essential methylation support, NMN Age Defend+™ is scientifically optimised for superior cellular repair, energy production, and long-term wellness.

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Natural Ingredients

Title

TWO NUTRA BROS - AGE SMART CHOICE

Energise. Protect. Restore. – Advanced Cellular Longevity with NMN Age Defend+™

Boosts NAD+ production with NMN for sustained energy & cellular repair. Enhances antioxidant defence with Trans-Resveratrol & Pterostilbene. Supports methylation & detox pathways with Trimethylglycine & Vitamin B12

Competitors

Sepismart SR™ Sustained Release Technology ensuring a steady supply of NAD+ precursors throughout the day.

Comprehensive Cellular Support- synergistic formula that supports longevity, cellular repair, and optimal methylation.

Clinically Backed Dosages – Each serving is carefully formulated with science-backed ingredient levels to deliver maximum efficacy.

Pure & Transparent Formula – We use only high-quality, vegan-friendly ingredients with no synthetic additives, preservatives, or unwanted excipients.

Targeted Longevity & Energy Formula – NMN Age Defend+™ is designed for comprehensive cellular health boosting energy.

100% Natural

Vegan

Recyclable

Cruelty Free

Additive Free

Lab-Tested

Frequently Asked Questions

How does NMN Age Defend+™ help with aging and energy levels?

NMN Age Defend+™ boosts NAD+ production through NMN, supporting cellular energy, repair, and mitochondrial function, all crucial for maintaining youthfulness and vitality.

How is NMN Age Defend+™ different from regular NMN supplements?

Unlike standard NMN supplements, NMN Age Defend+™ combines NMN with Resveratrol, Pterostilbene, Quercetin, and TMG for a comprehensive approach to longevity, brain function, and heart health.

When should I take NMN Age Defend+™ for the best results?

For maximum absorption, take 1–3 capsules daily, preferably between meals, with water.

Can I take NMN Age Defend+™ with other supplements?

Yes! Age Defend+™ pairs well with CoQ10, Omega-3s, and Vitamin D for enhanced mitochondrial and cardiovascular support.

Is NMN Age Defend+™ vegan and free from common allergens?

Yes! It’s 100% vegan, gluten-free, soy-free, and non-GMO, with no artificial additives.

How long does it take to see benefits?

While some users notice improved energy and mental clarity within a few weeks, cellular benefits accumulate over time—best results are seen with consistent use over 2–3 months.

Does Age Defend+™ support brain health?

Yes! Pterostilbene and Vitamin B12 contribute to cognitive function, neuroprotection, and mood balance.

Can I take NMN Age Defend+™ long-term?

Absolutely! Long-term NMN supplementation is safe and beneficial for maintaining cellular function, energy metabolism, and longevity.

Always consult your health professional before taking any supplementation.

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Organic

Sulfate-Free

Paraben-Free

100% Vegan

Cruelty Free

Lab-Tested

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NMN Age Defend+

£59.99